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What You Need to Know About Inflammation
Foods that Help Combat Inflammation
The Cleveland Clinic
Foundation.

Figure 1. When inflammation occurs normally, chemicals from
the body’s white blood cells are released to protect us from
foreign substances. Sometimes, however, the white blood cells
and their inflammatory chemicals cause damage to the body’s
tissues.
What is inflammation?
Inflammation is a process by which the body’s white blood cells
and chemicals protect us from infection and foreign substances
such as bacteria and viruses.
In some diseases, however, the body’s defense system (immune
system) inappropriately triggers an inflammatory response when
there are no foreign substances to fight off. In these diseases,
called autoimmune diseases, the body’s normally protective
immune system causes damage to its own tissues. The body
responds as if normal tissues are infected or somehow abnormal.
What diseases are associated with inflammation?
Some, but not all, types of arthritis are the result of
misdirected inflammation. Arthritis is a general term that
describes inflammation in joints. Some types of arthritis
associated with inflammation include:
·
Rheumatoid arthritis
·
Shoulder tendinitis or bursitis
·
Gouty arthritis
·
Polymyalgia rheumatica
Other painful conditions of the joints and musculoskeletal
system that are not associated with inflammation include
osteoarthritis, fibromyalgia, muscular low back pain and
muscular neck pain.
What are the symptoms of inflammation?
Inflammation is characterized by:
·
Redness
·
Swollen joint that is warm to touch
·
Joint pain
·
Joint stiffness
·
Loss of joint function
Often, only a few of these symptoms are present.
Inflammation may also be associated with general "flu-like"
symptoms including:
·
Fever
·
Chills
·
Fatigue/loss of energy
·
Headaches
·
Loss of appetite
·
Muscle stiffness

Figure 2. Inflamed Joint
What causes the symptoms of inflammation?
When inflammation occurs, chemicals from the body’s white blood
cells are released into the blood or affected tissues in an
attempt to rid the body of foreign substances. This release of
chemicals increases the blood flow to the area and may result in
redness and warmth. Some of the chemicals cause leakage of fluid
into the tissues, resulting in swelling. The inflammatory
process may stimulate nerves and cause pain.
What are the results of joint inflammation?
The increased number of cells and inflammatory substances within
the joint cause irritation, wearing down of cartilage (cushions
at the end of bones) and swelling of the joint lining.
How are inflammatory diseases diagnosed?
Inflammatory diseases are diagnosed after careful evaluation of:
·
Complete medical history and physical exam
·
The location of painful joints
·
Presence of joint stiffness in the morning
·
Evaluation of other symptoms
·
Results of X-rays and other tests
Can inflammation affect internal organs?
Yes. Inflammation can affect organs as part of an autoimmune
disorder. The type of symptoms depends on which organs are
affected. For example:
· Inflammation of the heart (myocarditis) may
cause shortness of breath or leg swelling
· Inflammation of the small tubes that
transport air to the lungs may cause an asthma attack
· Inflammation of the kidneys (nephritis) may
cause high blood pressure or kidney failure
· Inflammation of the large intestine
(colitis) may cause cramps and diarrhea
Pain may not be a primary symptom of the inflammatory
disease, since many organs do not have many pain-sensitive
nerves. Treatment of organ inflammation is directed at the cause
of inflammation whenever possible.
How are inflammatory joint diseases treated?
There are a number of treatment options for inflammatory
diseases including medications, rest and exercise, and surgery
to correct joint damage. The type of treatment prescribed will
depend on several factors including the type of disease, the
person’s age, type of medications he or she is taking, overall
health, medical history and severity of symptoms.
The goals of treatment are to:
·
Avoid or modify activities that aggravate
pain
·
Relieve pain through analgesics
(pain-relieving medications) and anti-inflammatory
medications
·
Maintain joint movement and muscle strength
through physical therapy
·
Decrease stress on the joints by using
braces, splints or canes as needed
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